Actively Recruiting
A Study of SHR-4610 Injection in Patients With Advanced Solid Tumors
Led by Shanghai Shengdi Pharmaceutical Co., Ltd · Updated on 2026-01-09
258
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is an open, multicenter Phase I/II clinical trial, divided into two stages: dose exploration (including dose escalation and dose extension) and efficacy extension.
CONDITIONS
Official Title
A Study of SHR-4610 Injection in Patients With Advanced Solid Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects must voluntarily agree to participate in the trial and sign a written informed consent form
- Age range: 18-75 years old, both male and female are welcome
- Patients with histologically or cytologically confirmed unresectable locally advanced or metastatic solid tumors which is relapsed or refractory to standard treatment, or lack of standard treatment
- Have at least one measurable tumor lesion per RECIST v1.1
- ECOG performance status of 0-1
- Life expectancy 262 12 weeks
- Adequate bone marrow and organ function
You will not qualify if you...
- Patients with active central nervous system metastases or meningeal metastases
- Systemic antitumor therapy was received 4 weeks before the start of the study
- Moderate or severe ascites with clinical symptoms; Uncontrolled or moderate or higher pleural effusion or pericardial effusion
- Have poorly controlled or severe cardiovascular disease
- Subjects with active hepatitis B or active hepatitis C
- Adverse reactions of previous anti-tumor treatment have not recovered to Grade 261 per NCI-CTCAE v5.0
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Zhejiang Cancer Hospital
Hangzhou, Zhejiang, China, 310022
Actively Recruiting
Research Team
Y
Yunpeng Jin
CONTACT
Y
Yuting Wang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
6
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