Actively Recruiting
A Study of Sintilimab Combined With Chemotherapy for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma
Led by Fujian Cancer Hospital · Updated on 2024-06-18
30
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is aimed to evaluate the efficacy and safety of sintilimab combined with chemotherapy (docetaxel+cisplatin+5-fluorouracil, DCF) in neoadjuvant treatment of locally advanced esophageal squamous cell carcinoma.
CONDITIONS
Official Title
A Study of Sintilimab Combined With Chemotherapy for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years
- Diagnosis of esophageal squamous cell carcinoma confirmed by biopsy
- Primary tumor located in the middle of the esophagus with stage T1b-3N1-3M0/M1 or T3N0M0 by CT/MRI/EUS (AJCC 8th edition)
- At least one measurable lesion
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 1
- Adequate organ function
You will not qualify if you...
- Active cancer within the past 5 years other than the study tumor or cured localized tumors like resected basal or squamous cell carcinoma, superficial bladder cancer, cervical carcinoma in situ, or breast cancer
- High risk of bleeding or perforation due to tumor invasion of adjacent organs such as the aorta or trachea, or presence of fistula
- Prior anti-tumor therapy for the esophageal cancer, including radiotherapy, chemotherapy, immunotherapy, or traditional Chinese medicine therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fujian Cancer Hospital
Fuzhou, Fujian, China, 350014
Actively Recruiting
Research Team
S
Shuoyan Liu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here