Actively Recruiting

Phase 2
Age: 12Years - 65Years
All Genders
NCT06525597

Study of Stapokibart Injection in Patients With Allergic Rhinitis

Led by Keymed Biosciences Co.Ltd · Updated on 2024-11-08

120

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a Randomized, Double-blind, Placebo-controlled phase II clinical study evaluating the efficacy and safety of Stapokibart injection in patients with allergic rhinitis.

CONDITIONS

Official Title

Study of Stapokibart Injection in Patients With Allergic Rhinitis

Who Can Participate

Age: 12Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to understand the study and voluntarily sign the Informed consent form.
  • Diagnosed Allergic Rhinitis according to the Criteria stated in the Chinese Guidelines for the Diagnosis and Treatment of Allergic Rhinitis (2022, Revised Edition).
  • Subjects with asthma must be evaluated by the researcher as having a stable condition.
  • Has a positive skin prick test (SPT) or positive antigen-specific serum immunoglobulin E (IgE).
Not Eligible

You will not qualify if you...

  • Use of anti-interleukin 4 receptor alpha subunit (IL-4Rb1) monoclonal antibody, thymic stromal lymphopoietin (TSLP) monoclonal antibody, anti-IgE monoclonal antibody, other monoclonal antibodies, or other biologics within 10 weeks or 5 half-lives (whichever is longer) prior to the screening visit.
  • Use of any investigational product within 4 weeks prior to the screening visit or planning to participate in other clinical studies during this study.
  • Forced expiratory volume in 1 second (FEV1) 64 50% of the predicted value during the screening/run-in period.
  • Have acute sinusitis, nasal infection, or upper respiratory tract infection at screening or within 2 weeks prior to screening.
  • Have received a live-attenuated vaccine within 12 weeks prior to randomization or planning to receive one during the study.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beijing Tongren Hospital, CMU

Beijing, Beijing Municipality, China

Actively Recruiting

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Research Team

Q

Qian Jia

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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