Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT07236788

Study on Supplement of Intravenous Ferric Derisomaltose to Prevent Anemia and Improve the Quality of Life in Obese Patients With Iron Deficiency.

Led by China-Japan Friendship Hospital · Updated on 2025-11-19

200

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aimed to explore the effects of preoperative intravenous isomaltose iron supplementation versus placebo on postoperative Hb improvement, prevention of postoperative anemia, and improvement in quality of life in patients undergoing bariatric surgery.

CONDITIONS

Official Title

Study on Supplement of Intravenous Ferric Derisomaltose to Prevent Anemia and Improve the Quality of Life in Obese Patients With Iron Deficiency.

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Baseline hemoglobin: Men 10-14 g/dL, Women 10-13 g/dL
  • Iron deficiency with serum ferritin less than 100 µg/L and transferrin saturation less than 20%
  • Body mass index (BMI) greater than 30 kg/m2
Not Eligible

You will not qualify if you...

  • Known severe hypersensitivity to parenteral iron supplements
  • Mean corpuscular volume (MCV) greater than 100 fL
  • Received intravenous iron infusion within the past 3 months
  • Presence of tumors
  • Iron overload or other blood disorders
  • Infectious diseases such as hepatitis B
  • Moderately impaired liver function including decompensated cirrhosis or hepatitis with ALT, AST over 3 times upper normal limit
  • Acute or chronic infections, heart failure, or diseases affecting iron metabolism
  • Chronic kidney disease stage 3 or higher with glomerular filtration rate less than 60 ml/min
  • Pregnant or breastfeeding women
  • Acute infections, rheumatoid arthritis, or significant joint inflammation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

China-Japan Friendship Hospital

Beijing, China

Actively Recruiting

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Research Team

N

Nianrong Zhang Zhang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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