Actively Recruiting

Phase 3
Age: 21Years +
All Genders
NCT06703476

A Study of Surgical Techniques During Cystectomy

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-01-27

530

Participants Needed

7

Research Sites

205 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to look at two standard surgical techniques used during a radical cystectomy and see whether they influence outcomes such as length of stay in the hospital and infections after surgery. This trial will evaluate whether the following surgical methods influence outcomes: A ureteral stent is a thin tube that is placed in the ureter to drain urine from the kidney. Ureteral stents are often used to promote urine drainage after radical cystectomy, but may come at risk of urinary tract infection. Alvimopan is a standard drug used to promote return of bowel function following surgery. Doctors do not know whether alvimopan is beneficial in current clinical practice. The surgeon will decide whether participants will receive a stent and/or alvimopan, but if they are unsure what the best approach is, a surgical technique has been assigned by chance to them.

CONDITIONS

Official Title

A Study of Surgical Techniques During Cystectomy

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 21 years or older scheduled for radical cystectomy to treat bladder cancer with a participating surgeon at MSK
Not Eligible

You will not qualify if you...

  • Patients on chronic opioid therapy are not eligible to receive alvimopan and are excluded from that part of the trial

AI-Screening

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Trial Site Locations

Total: 7 locations

1

Memorial Sloan Kettering at Basking Ridge (Consent Only)

Basking Ridge, New Jersey, United States, 07920

Actively Recruiting

2

Memorial Sloan Kettering Monmouth (Consent Only)

Middletown, New Jersey, United States, 07748

Actively Recruiting

3

Memorial Sloan Kettering Bergen (Consent Only)

Montvale, New Jersey, United States, 07645

Actively Recruiting

4

Memorial Sloan Kettering Suffolk-Commack (Consent Only)

Commack, New York, United States, 11725

Actively Recruiting

5

Memorial Sloan Kettering Westchester (Consent Only)

Harrison, New York, United States, 10604

Actively Recruiting

6

Memorial Sloan Kettering Cancer Center (All Protocol Activites)

New York, New York, United States, 10065

Actively Recruiting

7

Memorial Sloan Kettering Nassau (Consent Only)

Rockville Centre, New York, United States, 11553

Actively Recruiting

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Research Team

A

Alvin Goh, MD

CONTACT

B

Bernard Bochner, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

TREATMENT

Number of Arms

2

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A Study of Surgical Techniques During Cystectomy | DecenTrialz