Actively Recruiting

Phase 1
Age: 18Years - 55Years
All Genders
Healthy Volunteers
NCT07307274

A Study of SYNT-101 to Test Safety, Tolerability and Pharmacodynamics of SYNT-101 in Healthy and Overweight Adults

Led by Syntis Bio · Updated on 2026-04-29

64

Participants Needed

1

Research Sites

50 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A Phase 1, single-center, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and pharmacodynamics of single and multiple dose regimens of SYNT-101 in healthy and overweight adults.

CONDITIONS

Official Title

A Study of SYNT-101 to Test Safety, Tolerability and Pharmacodynamics of SYNT-101 in Healthy and Overweight Adults

Who Can Participate

Age: 18Years - 55Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to understand the study purpose and risks
  • Adults aged 18 to 55 years at screening
  • Medically healthy without significant abnormalities
  • Have suitable venous access for blood sampling
  • Willing and able to follow study assessments and schedule
Not Eligible

You will not qualify if you...

  • Known allergy to SYNT-101 or its ingredients
  • History of anaphylaxis or significant allergy affecting participation
  • History or presence of significant cardiovascular, lung, liver, kidney, blood, hormonal, immune, skin, psychiatric, or neurological diseases or disorders
  • Any acute illness within the past 3 months deemed relevant by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Veritus Research

Bayswater, Victoria, Australia

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

2

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