Actively Recruiting

Phase 3
Age: 18Years - 80Years
All Genders
NCT06803030

Study of Tamsulosin, Solifenacin and Mirabegron in Alleviating Ureteral Stent-related Symptoms

Led by Bir Hospital · Updated on 2025-09-08

189

Participants Needed

1

Research Sites

69 weeks

Total Duration

On this page

Sponsors

B

Bir Hospital

Lead Sponsor

N

Nepal Health Research Council

Collaborating Sponsor

AI-Summary

What this Trial Is About

A comparative study on the efficacy of Tamsulosin, Solifenacin and Mirabegron in alleviating ureteral stent-related symptoms: a randomized controlled trial.

CONDITIONS

Official Title

Study of Tamsulosin, Solifenacin and Mirabegron in Alleviating Ureteral Stent-related Symptoms

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 19 to 80 years
  • Underwent unilateral retrograde rigid ureteroscopy or retrograde intrarenal surgery
  • Planned ureteric stent insertion for urinary tract stones
Not Eligible

You will not qualify if you...

  • Use of alpha-blockers, anticholinergics, corticosteroids, calcium channel blockers, or analgesics
  • Undergoing percutaneous nephrolithotomy, open or laparoscopic ureteric surgery
  • Neurogenic bladder, overactive bladder syndrome, neurological or psychiatric diseases
  • Preoperative febrile urinary tract infection
  • Pregnancy or breastfeeding
  • Having a single kidney
  • Moderate or severe cardiovascular or cerebrovascular disease
  • Hepatic dysfunction
  • History of pelvic surgery or irradiation
  • History of bladder or prostate surgery
  • Acute medical conditions affecting pain score (e.g., acute pancreatitis, gastroenteritis, musculoskeletal disorders)
  • Allergy to any medication

AI-Screening

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Trial Site Locations

Total: 1 location

1

NAMS, Bir Hospital

Kathmandu, Bagmati, Nepal, 44600

Actively Recruiting

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Research Team

B

Baikuntha Adhikari, MCh

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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