Actively Recruiting
A Study to Test the Safety and Tolerability of SBO-154 in Patients With Advanced Solid Tumors.
Led by Sun Pharma Advanced Research Company Limited · Updated on 2026-01-22
177
Participants Needed
11
Research Sites
259 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a Phase 1 study of SBO-154 in patients with advanced cancers who are unable to tolerate or have not previously responded to standard therapy available in the country. The study involves multiple doses and takes place at several centers.
CONDITIONS
Official Title
A Study to Test the Safety and Tolerability of SBO-154 in Patients With Advanced Solid Tumors.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willing and able to give written and dated informed consent (or legally acceptable representative/impartial witness when applicable) and available for the entire study
- Willing and able to comply with scheduled visits, treatment plan, laboratory testing, study procedures, and restrictions, and accessible for follow-up
- Has locally recurrent or metastatic disease (except sarcomas) which has relapsed or progressed following local standard treatment, or for which no standard treatment is available
- Has a life expectancy of at least 3 months
You will not qualify if you...
- Any major surgery within 4 weeks before SBO-154 administration
- Evidence of organ dysfunction or any clinically significant abnormality on physical examination
- Known or suspected history of significant drug abuse
- Has an uncontrolled infection needing intravenous antibiotics, antivirals, or antifungals
- Known or suspected excessive alcohol intake in the past 12 months
- Positive urine pregnancy test (if applicable) or positive serology tests for HIV, HCV, or HBsAg (except those with resolved Hepatitis B or C)
- History of allergy or hypersensitivity to biological agents or drugs related to SBO-154
- Received another investigational agent within 30 days or 5 half-lives before SBO-154 administration
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 11 locations
1
Honorhealth Research Institute
Scottsdale, Arizona, United States, 85258
Actively Recruiting
2
Sarcoma Oncology Research Center
Santa Monica, California, United States, 90403
Actively Recruiting
3
Yale University - Yale Cancer Center
New Haven, Connecticut, United States, 06510
Not Yet Recruiting
4
Hope And Healing Cancer Services, Llc
Hinsdale, Illinois, United States, 60521
Actively Recruiting
5
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
6
Scientia Clinical Research
Randwick, New South Wales, Australia, 2031
Actively Recruiting
7
Sunshine Coast University Private Hospital
Birtinya, Queensland, Australia, 4557
Actively Recruiting
8
Cancer Research South Australia
Adelaide, South Australia, Australia, 5000
Actively Recruiting
9
Tata Memorial hospital
Mumbai, Maharashtra, India, 400012
Not Yet Recruiting
10
Noble Hospital Pvt. Ltd.
Pune, Maharashtra, India, 411013
Actively Recruiting
11
All India Institute for Medical Sciences
Delhi, New Delhi, India, 110029
Actively Recruiting
Research Team
D
Dr. Sandeep Inamdar
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
1
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