Actively Recruiting
A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment
Led by Dr. Willmar Schwabe GmbH & Co. KG · Updated on 2026-04-23
400
Participants Needed
30
Research Sites
109 weeks
Total Duration
On this page
Sponsors
D
Dr. Willmar Schwabe GmbH & Co. KG
Lead Sponsor
B
Beijing Tiantan Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if Extract of Ginkgo Biloba Leaves Tablets help improve thinking and memory in people aged 55 years and older who had an ischemic stroke (a type of stroke caused by a blocked blood vessel in the brain). It will also look at how safe the Extract of Ginkgo Biloba Leaves Tablets are. The main questions it aims to answer are: * Do the Extract of Ginkgo Biloba Leaves Tablets help people with memory or thinking problems after an ischemic stroke? * What medical problems do people have when taking the Extract of Ginkgo Biloba Leaves Tablets ? Researchers will compare people who take the Extract of Ginkgo Biloba Leaves Tablets along with their usual post-stroke treatment to people who only receive their usual post-stroke treatment. Participants will: * Have had an ischemic stroke confirmed by MRI (Magnet Resonance Imaging, a magnetic scan that helps seeing inside the body in great detail) 7 to 14 days before joining the study * Take Extract of Ginkgo Biloba Leaves Tablets (240 mg per day) in addition to usual post-stroke treatment for 12 months, or receive only usual post-stroke treatment for 12 months * Be treated initially at hospitals across China * Visit the clinic 4, 26, and 52 weeks following the baseline for checkups and tests, and receive follow-up calls after 12 and 38 weeks.
CONDITIONS
Official Title
A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female participants aged 55 years or older who gave informed consent
- Non-disabling acute ischemic stroke confirmed by MRI, with NIHSS score 5 or less and mRS score 2 or less at screening
- Cognitive impairment shown by Montreal Cognitive Assessment score below 23 for up to 12 years of education or below 22 for more than 12 years of education
- Sufficient Chinese language skills to understand questions, complete questionnaires, and undergo neuropsychological testing
You will not qualify if you...
- Participation in another experimental drug trial currently or within 4 weeks before enrollment
- Severe speech, movement, vision, hearing, or language difficulties that prevent cooperation or test performance
- Pre-stroke cognitive impairment or major neurocognitive disorders such as dementia
- Cardiogenic ischemic stroke, atrial fibrillation, or conditions requiring anticoagulants
- Need for thrombolytic treatment at screening or first visit
- Stroke with hemorrhagic transformation
- Use of traditional Chinese medicines
- Major neurological disorders including brain tumors, Parkinson's disease, epilepsy, and others
- Major depression or generalized anxiety disorder
- Active malignant disease
- Alcohol addiction or substance abuse
- Known allergy to Ginkgo biloba or ingredients of the study drug
- Inability to attend scheduled follow-ups due to hospitalization or nursing care
- Severe comorbid conditions with life expectancy under 12 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 30 locations
1
The People's Hospital of Anyang City
Anyang, China
Actively Recruiting
2
Baotou Central Hospital
Baotou, China
Actively Recruiting
3
Tiantan Hospital
Beijing, China
Actively Recruiting
4
Beipiao Central Hospital
Beipiao, China
Actively Recruiting
5
Benxi Central Hospital
Benxi, China
Actively Recruiting
6
The First People's Hospital of Chenzhou
Chenzhou, China
Actively Recruiting
7
Affiliated Hospital of Chifeng University
Chifeng, China
Active, Not Recruiting
8
Dalian Lvshunkou District Traditional Chinese Medicine Hospital
Dalian, China
Actively Recruiting
9
Dalian University Affiliated Xinhua Hospital
Dalian, China
Actively Recruiting
10
Affiliated Hospital of Hebei University
Hebei, China
Actively Recruiting
11
The Second Hospital of Hebei Medical University
Hebei, China
Actively Recruiting
12
The Second Affiliated Hospital of Henan University of Science and Technology
Henan, China
Actively Recruiting
13
The First Affiliated Hospital of Jiamusi University
Jiamusi, China
Actively Recruiting
14
Liaocheng People´s Hospital
Liaocheng, China
Actively Recruiting
15
Liuzhou Workers´ Hospital
Liuzhou, China
Actively Recruiting
16
Luoyang Central Hospital
Luoyang, China
Actively Recruiting
17
Puyang Oilfield General Hospital
Pujiang, China
Actively Recruiting
18
Qilu Hospital of Shandong University
Qingdao, China
Actively Recruiting
19
First Hospital of Shanxi Medical University
Shanxi, China
Active, Not Recruiting
20
Second Hospital of Shanxi Medical University
Shanxi, China
Actively Recruiting
21
Shanxi Cardiovascular Hospital
Shanxi, China
Actively Recruiting
22
The First People's Hospital Of Shenyang
Shenyang, China
Actively Recruiting
23
Siping City Central People's Hospital
Siping, China
Actively Recruiting
24
Suining Central Hospital
Suining, China
Actively Recruiting
25
Weifang People´s Hospiztal
Weifang, China
Actively Recruiting
26
Zhongnan Hospital of Wuhan University
Wuhan, China
Active, Not Recruiting
27
Wuxi No.2 People's Hospital
Wuxi, China
Actively Recruiting
28
Yantaishan Hospital
Yantai, China
Actively Recruiting
29
Zhumadian Central Hospital
Zhumadian, China
Actively Recruiting
30
Zibo Municipal Hospital
Zibo, China
Actively Recruiting
Research Team
C
Clinical Project Manager
CONTACT
S
Senior Medical Advisor, M.D., Ph.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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