Testing Topical Herbal Plasters to Improve Pain Relief and Reduce Opioid Use in Adults with Cancer Pain

What this Trial Is About

Researchers are evaluating whether Tibetree pain-relieving herbal plasters, applied topically, can be a helpful addition to standard opioid therapy for managing pain in people with current or past cancer. This Phase 1 study aims to find out if using these herbal plasters is practical and effective for localized pain relief in patients already using opioids. The study is sponsored by Memorial Sloan Kettering Cancer Center and focuses on cancer patients experiencing specific types of pain. Participants will be randomly assigned to one of two groups one group will use the Tibetree herbal plasters once daily for up to 8 hours over 7 days, while the other group will be on a waitlist control. After a 7-day waiting period, those in the waitlist control group will then begin using the herbal plasters for another 7 days. The study compares these treatment periods to evaluate adherence, satisfaction, and pain relief. During the study, participants enrollment, treatment adherence, and completion of assessments will be monitored over 2 years. Pain severity and treatment satisfaction will be measured up to day 7. Participants will be asked to follow study procedures, including randomization and use of the plaster on their worst pain area. Safety and effectiveness data will be collected through questionnaires and pain rating scales, with the entire study extending over multiple years for follow-up.

A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain