Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT07447856

A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-03-04

150

Participants Needed

7

Research Sites

101 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The are doing this study to find out whether using topical (on the skin) herbal plasters, Tibetree pain- relieving plasters (PRPs), can be an effective addition to standard opioid therapy for pain management. The researchers will look at whether the Tibetree PRPs are a practical (feasible) and effective way of managing localized pain (pain that is limited to a certain area) in people who are currently taking opioids. Participants in this study will have cancer or have had it in the past.

CONDITIONS

Official Title

A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • English speaking and aged 18 years or older
  • Diagnosed with any type or stage of cancer
  • Able to walk and have a Karnofsky Performance Status of 60 or higher
  • Have musculoskeletal, bone metastasis, or visceral/abdominal pain
  • Worst pain score of 4 or above on a 0-10 scale in the past week
  • Currently using short-term oral opioids like oxycodone or morphine
  • Willing and able to follow all study procedures including randomization
  • Able to understand and sign the informed consent form
Not Eligible

You will not qualify if you...

  • Unwilling to reduce opioid use if pain improves
  • Have generalized musculoskeletal pain such as fibromyalgia as main pain source
  • Have severe skin disorders like eczema, psoriasis, xerosis, dermatitis, or adhesive allergy
  • Have open wounds, infections, or skin trauma on the painful area
  • Have history of skin sensitivity or allergic reactions to adhesives, patches, plants, or herbs
  • Unwilling to stop current localized topical pain treatments like lidocaine patch
  • Started or changed pain management treatments within 1 week before enrollment
  • Plan to start or change pain treatments within 2 weeks after enrollment
  • Started or changed cancer treatments within 1 week before enrollment
  • Plan to start or change cancer treatments within 2 weeks after enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

Basking Ridge, New Jersey, United States, 07920

Actively Recruiting

2

Memorial Sloan Kettering Monmouth (All Protocol Activities)

Middletown, New Jersey, United States, 07748

Actively Recruiting

3

Memorial Sloan Kettering Bergen (All Protocol Activities)

Montvale, New Jersey, United States, 07645

Actively Recruiting

4

Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities)

Commack, New York, United States, 11725

Actively Recruiting

5

Memorial Sloan Kettering Westchester (All Protocol Activities)

Harrison, New York, United States, 10604

Actively Recruiting

6

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, United States, 10065

Actively Recruiting

7

Memorial Sloan Kettering Nassau (All Protocol Activities)

Rockville Centre, New York, United States, 11553

Actively Recruiting

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Research Team

J

Jun Mao, MD, MSCE

CONTACT

K

Kevin Liou, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain | DecenTrialz