Actively Recruiting
Study of Thoracic Ultrasound As a Response to the Closure of Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2024-10-15
50
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The diagnostic hypothesis is based on the evidence that, while the functional closure of the PDA (Patent Ductus Arteriosus) occurs within a few hours after birth, anatomical closure may take several weeks. The functional closure of the PDA can be extremely sensitive to variations in blood oxygen tension and the hemodynamic instability of preterm infants. Therefore, echocardiographic evaluation and ductal diameter at a single point in time (such as during PDA echocardiography) may not correlate with transductal blood flow. Assessing the variation in the amount of pulmonary interstitial fluid using LUS (lung ultrasound score) could be an early predictive parameter for the closure or non-closure of hsPDA (hemodynamically significant PDA).
CONDITIONS
Official Title
Study of Thoracic Ultrasound As a Response to the Closure of Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Neonates under 28 days of life
- Patients eligible for hsPDA closure treatment according to standard clinical practice
You will not qualify if you...
- Neonates with congenital heart diseases (except for PDA and patent foramen ovale)
- Neonates with pneumothorax
- Neonates with pulmonary hemorrhage
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, roma, Italy, 00168
Actively Recruiting
Research Team
A
Angela Paladini
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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