Time-Restricted Eating and Motivational Support to Reduce Heart and Metabolic Risk in Adult Survivors of Childhood Cancer

What this Trial Is About

Researchers are evaluating whether combining motivational sessions with time-restricted eating TRE can help adult survivors of childhood cancer lose weight and reduce cardiometabolic risk. The study compares this approach to the usual care, which consists of reviewing educational materials and monthly weight measurements. This research focuses on weight management and does not provide treatment for any cancer or disease. Participants in the intervention group will gradually build up to a daily 16-hour fasting period, avoiding calorie-containing foods and drinks during this time. They will receive motivational coaching calls bi-weekly for the first three months, then monthly, along with daily text reminders and monthly weight checks. The comparison group will receive standard educational materials and monthly weight monitoring through an online platform. During the study, participants will complete questionnaires about health beliefs, worry, and physical activity. They will also provide dried blood spot samples at home to measure glucose, insulin, hemoglobin A1c, and lipids. Weight and other body measurements will be collected remotely. The main outcome is the percent change in weight after 12 months, with additional measures including changes in glucose, insulin, and hemoglobin A1c levels. The study will monitor participants over a 12-month period with regular check-ins and data collection.

A Study of Time-Restricted Eating in Childhood Cancer Survivors