Actively Recruiting

Phase Not Applicable
Age: 6Years +
All Genders
NCT05673915

Study of Transcranial Direct Current Stimulation to Treat Epilepsy

Led by Mayo Clinic · Updated on 2026-01-28

30

Participants Needed

1

Research Sites

189 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.

CONDITIONS

Official Title

Study of Transcranial Direct Current Stimulation to Treat Epilepsy

Who Can Participate

Age: 6Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of generalized onset or focal epilepsy or sleep-related epileptic encephalopathy.
  • Estimated to have at least 2 countable seizures per month or spike-wave index 250%.
  • Has not had control with at least 2 anti-seizure medicines.
  • Able to maintain a constant medication for duration of the study (rescue meds allowed).
  • Subject or legally authorized representative is able to understand consent and keep a seizure diary in English.
Not Eligible

You will not qualify if you...

  • A disease likely to progress over course of the study.
  • Psychogenic non-epileptic seizures.
  • Suicide attempt or psychiatric hospitalization past 2 years.
  • A skin condition interfering with scalp electrodes or allergy to silver.
  • Women will verify not pregnant, and if applicable, have a serum pregnancy test.
  • Implanted devices (e.g. pacemakers)-except VNS, which is allowed.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic Minnesota

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

P

Precylla Ruiz

CONTACT

I

Izzie Meunier

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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