Actively Recruiting

Age: 18Years +
All Genders
NCT06749015

A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)

Led by Fudan University · Updated on 2024-12-27

100

Participants Needed

1

Research Sites

291 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Previous studies have shown that BRAFV600E mutant mCRC patients have a shorter survival time than BRAF wild type mCRC patients. For Chinese patients, however, it remains unclear about the BRAF gene mutation rate, diagnosis, prognosis and survival data in people with BRAFV600E mutant mCRC . This real-world, multicenter non-interventional study (NIS) will describe the mutation rate, treatment patterns, effectiveness and safety of current treatment regimens in BRAFV600E mutant mCRC patients in China.

CONDITIONS

Official Title

A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of histologically or cytologically confirmed colorectal cancer that is metastatic and unresectable
  • Presence of BRAFV600E mutation in tumor tissue confirmed by a local test
Not Eligible

You will not qualify if you...

  • History of chronic inflammatory bowel disease, chronic diarrhea, or recurrent bowel obstruction
  • Presence of symptomatic brain metastases
  • Active severe infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China, 200032

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC) | DecenTrialz