Actively Recruiting
A Multicenter Observational Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer
Led by Fudan University · Updated on 2024-12-27
100
Participants Needed
1
Research Sites
291 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with metastatic colorectal cancer (mCRC) who have the BRAFV600E mutation generally experience shorter survival times compared to those with BRAF wild-type mCRC. However, data on the mutation rate, diagnosis, prognosis, and survival for Chinese patients with BRAFV600E mutant mCRC is limited. This study aims to provide real-world information on these aspects for this patient group in China. This is a multicenter, non-interventional observational study that will monitor treatment patterns, effectiveness, and safety of current therapies used for BRAFV600E mutant mCRC patients. There is no experimental treatment administered, as the study collects data based on existing clinical care practices. Participants will be followed to assess progression-free survival over 6 months. Researchers will gather information on treatments received, mutation status, and safety outcomes. The study will help describe how patients are diagnosed and treated in routine care and how these treatments impact disease progression and patient safety.
CONDITIONS
Official Title
A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of histologically or cytologically confirmed colorectal cancer that is metastatic and unresectable
- Presence of BRAFV600E mutation in tumor tissue confirmed by a local test
You will not qualify if you...
- History of chronic inflammatory bowel disease, chronic diarrhea, or recurrent bowel obstruction
- Presence of symptomatic brain metastases
- Active severe infection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here