Actively Recruiting
A Study of Treatment-Related Toxicities and Quality of Life After Local Therapy in Chinese Breast Cancer Patients
Led by FangYi · Updated on 2025-09-12
3000
Participants Needed
3
Research Sites
194 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study, called PERSEVERE, examines how local treatment for early breast cancer affects people's health and daily lives over time. People who join the study will have early-stage breast cancer and receive treatment such as surgery and other therapies that are used before or after surgery. The study does not include people with late-stage (metastatic) breast cancer. Researchers want to learn about short- and long-term side effects that can happen during or after treatment. These may include tiredness, trouble sleeping, emotional distress, pain, or changes in heart or lung function. The study also looks at how these effects impact participants' quality of life. Participants will be asked to complete surveys about how they feel. They will also have health checks, such as heart tests, lung function tests, and blood samples. Tissue samples from surgery will also be collected. The goal is to understand better how different people respond to breast cancer treatment and find ways to support long-term recovery.
CONDITIONS
Official Title
A Study of Treatment-Related Toxicities and Quality of Life After Local Therapy in Chinese Breast Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 18 years or older
- Diagnosed with stage I, II, or III invasive breast cancer confirmed by pathology or cytology
- No signs of metastatic disease (cancer that has spread to other parts of the body)
- Scheduled to receive local treatment, including surgery and/or neoadjuvant or adjuvant therapy such as chemotherapy, radiation, hormone therapy, or targeted therapy
- Willing and able to complete health questionnaires and attend follow-up visits
- Has given written informed consent to join the study
You will not qualify if you...
- Have metastatic breast cancer or local recurrence
- Have already received curative treatment (surgery, chemotherapy, etc.) for the current breast cancer before joining the study
- Are currently pregnant or breastfeeding
- Have a history of another cancer within the past 5 years (except for non-melanoma skin cancer or in-situ cervical cancer)
- Are unable to participate in the study due to mental, physical, or legal reasons (for example, under legal guardianship or imprisonment)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, Beijing Municipality, China, 100021
Actively Recruiting
2
Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center
Shenzhen, Guangdong, China, 518116
Active, Not Recruiting
3
Shanxi Cancer Hospital
Taiyuan, Shanxi, China, 030013
Active, Not Recruiting
Research Team
Z
Zheng Qu, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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