Actively Recruiting
Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.
Led by University of Fujairah · Updated on 2025-11-26
45
Participants Needed
1
Research Sites
102 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate the effectiveness of intentional replantation (IR) as a treatment for single-rooted teeth diagnosed as hopeless due to true periodontic lesions. The study will assess changes in alveolar bone and periodontal tissues, symptom resolution, and patient-reported outcomes (satisfaction and quality of life) following the procedure. Cone beam computed tomography (CBCT) imaging will be used to track radiographic changes at baseline and 9 months, while clinical examinations will monitor symptom resolution, including pain, swelling, and tooth mobility. The study is a single-arm pre-test, post-test interventional design conducted at the College of Dentistry, University of Science and Technology Fujairah (new name: University of Fujairah). Participants will include adults aged 18-70 with single-rooted teeth deemed hopeless due to periodontic lesions. Participants will undergo intentional replantation, and data will be collected through clinical examinations, radiographic images, and patient questionnaires at baseline and 9 months. Statistical analysis will compare pre- and post-treatment outcomes using paired-samples t-tests or Wilcoxon signed-rank tests, depending on data normality. The study aims to provide a comprehensive evaluation of intentional replantation, contributing valuable insights into its clinical effectiveness for managing complex dental conditions.
CONDITIONS
Official Title
Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with American Society of Anesthesiologists physical status classification 1 or 2
- Radiographic bone loss of at least 50% around the targeted tooth
- Probing depth of at least 5 millimetres around the targeted tooth
- Grade III mobility (extreme mobility) of the targeted tooth according to Miller's classification
- Grade II mobility or less of adjacent teeth
- Distance between targeted and adjacent teeth less than 2 millimetres
- Patient prefers intentional replantation to extraction for tooth retention
You will not qualify if you...
- Previous history of failed intentional replantation
- Severe anatomical limitations in the treatment area
- Unwillingness to follow study follow-up protocols
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Dental Clinic, College of Dentistry, University of Fujairah,
Fujairah, Emirate of Fujairah, United Arab Emirates, 2202
Actively Recruiting
Research Team
N
Nabeel Ayappali Kalluvalappil, MDS
CONTACT
T
Tamer Hamed Hassan, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here