Actively Recruiting
A Study of Trilaciclib Combined With mFOLFIRINOX in the Treatment of Patients With Advanced Pancreatic Cancer
Led by The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Updated on 2024-02-23
30
Participants Needed
1
Research Sites
144 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To observe the incidence of chemotherapy-induced myelosuppression and the safety of Trilaciclib combined with mFOLFIRINOX in patients with advanced pancreatic cancer receiving first-line treatment.
CONDITIONS
Official Title
A Study of Trilaciclib Combined With mFOLFIRINOX in the Treatment of Patients With Advanced Pancreatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 75 years
- ECOG performance status of 0 or 1
- Expected survival of at least 12 weeks
- Diagnosed with pancreatic cancer confirmed by tissue or cell tests
- No prior anti-cancer therapy received
- Adequate major organ function as shown by neutrophil count ≥1.5×10⁹/L, hemoglobin ≥10 g/dL, and platelet count ≥100×10⁹/L within 7 days before treatment
- Biochemical tests meeting these standards: total bilirubin ≤1.5 times upper normal limit, ALT and AST ≤1.5 times upper normal limit, creatinine clearance ≥60 ml/min
- Use effective birth control if of reproductive age (including male patients with female partners)
- Voluntarily signed informed consent
- Expected to comply with study visits and procedures
You will not qualify if you...
- Received any systemic anti-cancer therapy before
- Pregnant or breastfeeding women; women of childbearing age must have a negative pregnancy test within 7 days before study entry
- Substance abuse or medical, psychological, or social factors that could interfere with informed consent or study participation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Affiliated Hospital of Nanjing University Medical School
Nanjing, Jiangsu, China, 210008
Actively Recruiting
Research Team
D
du juan, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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