Actively Recruiting

Phase 1
Age: 22Years +
All Genders
NCT05764954

A Study of Tumor-Treating Fields (TTFields) in People With Lung Adenocarcinoma

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-09

25

Participants Needed

7

Research Sites

208 weeks

Total Duration

On this page

Sponsors

M

Memorial Sloan Kettering Cancer Center

Lead Sponsor

N

NovoCure Ltd.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The researchers are doing this study to find out if treatment with TTFields using the NovoTTF-200T System is safe and practical (feasible) before surgical removal (resection) of lung adenocarcinoma (ADC). The researchers will also look at how the treatment may help the body's immune system to fight cancer.

CONDITIONS

Official Title

A Study of Tumor-Treating Fields (TTFields) in People With Lung Adenocarcinoma

Who Can Participate

Age: 22Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Provide written informed consent for the study
  • Be 22 years of age or older at the time of signing consent
  • Have clinical stage 1A2, 1A3, or IB biopsy-proven lung adenocarcinoma eligible for anatomical resection
  • Have a lung nodule larger than 1 cm suspected to be lung adenocarcinoma with a biopsy planned
  • If multiple nodules are present, one must meet the above criteria
  • Have no history of prior malignancy in the chest or have completed potentially curative therapy with no recurrence for 5 years
Not Eligible

You will not qualify if you...

  • Receiving therapy for another active cancer
  • History of cardiac arrhythmias or use of a pacemaker
  • Lung nodules smaller than 1 cm
  • Lung nodules that are pure ground glass opacities of any size
  • Lung nodules that are less than 50% solid of any size

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

Memorial Sloan Kettering Basking Ridge (Consent Only)

Basking Ridge, New Jersey, United States, 07920

Actively Recruiting

2

Memorial Sloan Kettering Monmouth (Consent Only)

Middletown, New Jersey, United States, 07748

Actively Recruiting

3

Memorial Sloan Kettering Bergen (Consent Only)

Montvale, New Jersey, United States, 07645

Actively Recruiting

4

Memorial Sloan Kettering Suffolk - Commack (Consent Only)

Commack, New York, United States, 11725

Actively Recruiting

5

Memorial Sloan Kettering Westchester (Consent Only)

Harrison, New York, United States, 10604

Actively Recruiting

6

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, United States, 10065

Actively Recruiting

7

Memorial Sloan Kettering Nassau (Consent Only)

Uniondale, New York, United States, 11553

Actively Recruiting

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Research Team

P

Prasad Adusumilli, MD

CONTACT

M

Matthew Bott, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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