Actively Recruiting
Study to Understand Novel Biomarkers in Researching Dementia
Led by Washington University School of Medicine · Updated on 2026-01-16
1800
Participants Needed
1
Research Sites
224 weeks
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to determine the relationships between amyloid, tau, and neurodegeneration biomarkers in the blood and the presence of Alzheimer's disease (AD) pathology, clinical cognitive decline, and diagnosis. We aim to understand how well blood-based biomarkers can diagnose and predict Alzheimer's disease, which will help to further develop and validate blood tests for the disease.
CONDITIONS
Official Title
Study to Understand Novel Biomarkers in Researching Dementia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 60 years of age
- 80% of newly enrolled participants will have symptoms of forgetfulness, mild cognitive impairment, mild dementia, or Alzheimer's disease as noted by medical chart or provider
- All SEABIRD participants are invited regardless of cognitive status
You will not qualify if you...
- Unable to perform one or more basic activities of daily living (eating, bathing, dressing, ambulating, toileting) due to cognitive impairment
- Uncontrolled hepatitis B, hepatitis C, or HIV at time of blood collection
- Taking a disease-modifying drug for Alzheimer's disease at enrollment
- Blood transfusion in the last three months
- Unwilling or unable to participate in all study activities
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
L
Lisa Soke
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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