Evaluating a Urine Test for Detecting Colorectal Cancer and Precancerous Polyps in Adults Across Africa

What this Trial Is About

Researchers are evaluating a urine test called the 3-metabolite biosensor to detect colorectal cancer CRC and precancerous polyps in adults living in Ghana, Tanzania, and South Africa. The study focuses on participants who either have symptoms of colorectal cancer, are undergoing screening colonoscopy, or have had recent colonoscopy or pathology results related to CRC or polyps. Participants will be observed using the 3-metabolite biosensor, which is designed to identify colorectal cancer and precancerous polyps from urine samples. The study includes individuals with various colonoscopy findings, including those with diagnosed CRC, adenomatous polyps, or no malignancy, and those presenting symptoms such as rectal bleeding. During the study, participants will provide urine samples for testing with the biosensor. Researchers will measure the sensitivity of the biosensor in detecting colorectal cancer and precancerous polyps over up to one year. Participants are asked to be willing to participate and meet the age criteria of 18 years or older. The study is observational and does not involve treatment interventions.

A Study of a Urine Test to Detect Colorectal Cancer