Actively Recruiting
A Study of Uveitis in Children Younger Than 18 Years of Age
Led by Jaeb Center for Health Research · Updated on 2026-05-08
300
Participants Needed
4
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to collect information about clinical features and treatment histories in children under 18 years who have uveitis. It seeks to understand how often different types of uveitis occur in children and the clinical and demographic characteristics of each subtype. The study focuses on both new and established cases of uveitis in pediatric patients. Participants are grouped into those with recent uveitis onset (within 6 months) and those with established uveitis (onset more than 6 months ago). Children with recent onset will have their medical charts reviewed over 12 months, while all participants complete a single enrollment visit with their doctor. The study does not involve any investigational treatments but observes children with active or inactive uveitis regardless of current or past treatment. During the enrollment visit, clinical data will be collected to measure the frequency of uveitis subtypes in children under 18. For recent onset cases, ongoing chart reviews over a year will provide additional information on disease progress and management. Participants' medical history, treatment status, and disease characteristics will be documented, contributing to a better understanding of pediatric uveitis. The study lasts for the enrollment period and an additional 12 months of observation for some children.
CONDITIONS
Brief Title
A Study of Uveitis in Children <18 Years of Age
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children younger than 17 years with uveitis onset within the last 6 months
- Children younger than 18 years with uveitis onset more than 6 months ago
- Diagnosis of any type of uveitis except traumatic and post-operative uveitis
- Active or inactive uveitis with any treatment status including current, prior, or no treatment but under surveillance
You will not qualify if you...
- Bilateral uveitis with different underlying causes
- Traumatic uveitis
- Post-operative uveitis
- Immediate family member who is an investigative site personnel or employee of the study sponsor
- Eye diseases related to retinoblastoma, Coat's disease, retinitis pigmentosa, inherited retinal degeneration, Juvenile xanthogranuloma (JXG), or leukemia/malignancy within the eye
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to approximately 5 years until study completion
Participants diagnosed with uveitis are observed to collect information on uveitis subtypes and disease activity.
Visits as per clinical care schedule
Trial Site Locations
Total: 4 locations
1
Department of Ophthalmology, Boston University School of Medicine
Boston, Massachusetts, United States, 02118
Actively Recruiting
2
Akron Children's Hospital
Akron, Ohio, United States, 44308
Actively Recruiting
3
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229
Actively Recruiting
4
Pediatric Ophthalmology Associates, Inc.
Columbus, Ohio, United States, 43205
Actively Recruiting
Research Team
J
Julianne Zawadzki, MSPH
R
Raymond Kraker, MSPH
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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