Actively Recruiting
A Study of V118E in Healthy Participants (V118E-003)
Led by Merck Sharp & Dohme LLC · Updated on 2026-02-27
126
Participants Needed
4
Research Sites
109 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are looking for new vaccines to prevent illnesses caused by a type of bacteria called Streptococcus pneumoniae. There are many different types of Streptococcus pneumoniae bacteria, called serotypes. Vaccines contain small parts of certain serotypes. These parts will not cause an infection but help the body create antibodies (proteins) to fight the bacteria. PREVNAR 20™ is a vaccine given to help to prevent disease from Streptococcus pneumoniae bacteria. Researchers designed a new vaccine, V118E, to help prevent disease from Streptococcus pneumoniae bacteria. The goal of this study is to learn how safe V118 formulation E is in Healthy Adults and how well people tolerate it.
CONDITIONS
Official Title
A Study of V118E in Healthy Participants (V118E-003)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be in good health before randomization
You will not qualify if you...
- Have had invasive pneumococcal disease or other culture-positive pneumococcal disease within 3 years before vaccination
- Have a history of significant endocrine, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological diseases including stroke and chronic seizures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Velocity Clinical Research, Hallandale Beach ( Site 0003)
Hallandale, Florida, United States, 33009
Actively Recruiting
2
QPS-MRA, LLC-Early Phase ( Site 0002)
South Miami, Florida, United States, 33143
Actively Recruiting
3
Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0004)
Springfield, Missouri, United States, 65802
Actively Recruiting
4
University of Texas Medical Branch ( Site 0001)
Galveston, Texas, United States, 77555-1115
Actively Recruiting
Research Team
T
Toll Free Number
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here