Actively Recruiting
Study of VEGF-A Targeting NIR-II Fluorescence Endoscopy in the Gastrointestinal Tract
Led by Institute of Automation, Chinese Academy of Sciences · Updated on 2025-05-13
30
Participants Needed
1
Research Sites
149 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study, the investigators are studying new ways to look for abnormal tissues of the gastrointestinal tract during an endoscopy. We are using a VEGF-A targeting fluorescent probe and a NIR-II fluorescent endoscope to help detect abnormal tissues that are hard to see by the naked eye. The main purposes of this study include: 1. To translate the NIR-II approach into the endoscopy, and understand its advantages and limitations on detecting abnormal tissues in gastrointestinal. 2. To validate whether topical administration of a targeting probe can stick to abnormal tissues and be detected by the NIR-II endoscope. 3. To validate the safety and effectiveness of the topical administration of VEGF-A targeting probes for clinical application.
CONDITIONS
Official Title
Study of VEGF-A Targeting NIR-II Fluorescence Endoscopy in the Gastrointestinal Tract
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Known or suspected gastrointestinal lesions
- Scheduled for a clinically-indicated endoscopy
- Mentally competent person, 18 years or older
- Approved to sign the informed consent
- Adequate potential for follow-up
You will not qualify if you...
- Known allergy or negative reaction to ICG or derivatives
- Undesirable function of heart, lung, kidney, or any other organs
- Enrolled in other trials in the past 3 months
- Pregnant or trying to conceive
- Unable to tolerate an endoscopy
- Medical or psychiatric conditions that compromise the patient's ability to give informed consent
- Considered inappropriate to be included by researchers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Lidan Fu
Beijing, Beijing Municipality, China, 100190
Actively Recruiting
Research Team
L
Lidan Fu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
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