Actively Recruiting

Age: 18Years - 40Years
FEMALE
NCT06124664

Study of Venous Outflow From the Lower Limbs in Patients With Pelvic Varicosities

Led by Pirogov Russian National Research Medical University · Updated on 2024-12-27

90

Participants Needed

1

Research Sites

84 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Compression therapy is basic treatment for chronic venous disease (CVD) of the lower limbs. Numerous studies have demonstrated the efficacy and safety of compression therapy in relieving symptoms such as pain, venous edema, leg heaviness and fatigue, as well as accelerating the healing of venous ulcers. It has been established that сompression therapy is indicated for patients with both minimally expressed manifestations of CVD and severe forms of the disease. At the same only one study has been conducted to assess the correction of venous outflow from the lower limbs and pelvis in patients with pelvic varicose vein (PVV) and pelvic congestion syndrome (PCS). However, the incidence of this pathology ranges from 15 to 30% in the female population. The cost to the healthcare system of treating these patients in the United States exceeds $2 billion. To date, the options and indications for compression therapy in patients with concomitant PVV and CVD have not been defined. The rational use of compression in this cohort of patients may contribute to the improvement of effective conservative treatment. In addition, inappropriate prescription of compression to patients with pelvic venous disease (which can be observed in real clinical practice) may discredit this simple, effective and safe therapeutic method. In addition, the research devoted to the problem of compression treatment of PVV will contribute to the development of new special compression products aimed at accelerating venous outflow from the pelvic organs. It can be assumed that this will serve as a stimulus for obtaining new data on the therapeutic effects of compression and create conditions for the creation of new technological directions in the production of compression knitwear.

CONDITIONS

Official Title

Study of Venous Outflow From the Lower Limbs in Patients With Pelvic Varicosities

Who Can Participate

Age: 18Years - 40Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient age from 18 to 40 years
  • Presence of pelvic varicose veins according to DUS data
  • Reflux in the pelvic veins for more than 1 second before this DUS
  • Reflux in the superficial veins of the lower limbs
Not Eligible

You will not qualify if you...

  • Menopause
  • Pregnancy
  • Postthrombotic disease
  • Suspicion of May-Turner syndrome
  • Ultrasound signs of nutcracker syndrome

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ananstsia Grishenkova

Moskva, Russia, 119049

Actively Recruiting

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Research Team

S

Sergey G Gavrilov, MD, PhD

CONTACT

A

Anatoly V Karalkin, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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