Study of Venous Outflow From the Lower Limbs in Patients With Pelvic Varicosities as a New Strategy for Compression Treatment of Pelvic Varicose Veins and Varicose Veins of the Lower Limb

What this Trial Is About

Researchers are investigating the effects of pelvic varicose veins (PVV) and pelvic congestion syndrome (PCS) on venous outflow from the lower limbs in women with chronic venous disease (CVD). This observational study aims to understand how symptomatic and asymptomatic PVV impact the clinical course of CVD and the potential role of compression therapy. The study addresses the relationship between pelvic and lower limb varicose veins, including their frequency, symptoms, and hemodynamic disturbances, to improve treatment strategies and develop targeted compression products. The study includes three groups: 40 women with symptomatic PVV without signs of CVD, 40 women with asymptomatic PVV showing signs of CVD, and 10 women with varicose veins of the lower limb without PVV or PCS. Participants undergo diagnostic tests including radionuclide venography and single-photon emission computed tomography (SPECT) to assess venous outflow and pelvic venous congestion. The study duration is from May 2023 to January 2024, focusing on measuring isotope transport time and the coefficient of pelvic venous congestion. Participants will be monitored through imaging studies and clinical assessments at baseline and after 10 days. Researchers will evaluate venous blood flow, pelvic vein reflux, and symptoms related to pelvic congestion. The main outcomes include the average transport time of an injected isotope and a quantitative pelvic venous congestion coefficient. These results will help clarify the role of compression therapy and venous outflow disorders in women with PVV and CVD, aiming to improve conservative treatment options and clinical management.

Study of Venous Outflow From the Lower Limbs in Patients With Pelvic Varicosities