Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
MALE
NCT06324071

Study to Verify the Efficacy of a Product Containing 125 mg of TetraSOD® for the Treatment of Male Infertility

Led by Fitoplancton Marino, S.L. · Updated on 2025-03-10

50

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

Sponsors

F

Fitoplancton Marino, S.L.

Lead Sponsor

F

Fundacio Clinic Barcelona

Collaborating Sponsor

AI-Summary

What this Trial Is About

TetraSOD® is a unique marine phytoplankton (Tetraselmis chuii) SOD-rich ingredient that is grown under patent-protected technology exclusively designed by the company Fitoplancton Marino, S.L. (Spain). In a previous pilot trial, the ability of TetraSOD® (dose: 250 mg/day) to improve semen characteristics in idiopathic infertile men after three months of treatment was assessed, revealing significant improvements in almost all of the analyzed parameters. In a further clinical trial close to finish (ClinicalTrials.gov Identifier: NCT04864314) using the same dose, such positive results have been tested again in a higher number of patients, and additional parameters have been included in order to gain insights into the sperm physiological changes that underpin the improvement in semen quality. In this new clinical trial, an intermediate dose (125 mg/day) is going to be tested in an attempt to determine a range of TetraSOD® dosage being clinically active for the treatment of male infertility.

CONDITIONS

Official Title

Study to Verify the Efficacy of a Product Containing 125 mg of TetraSOD® for the Treatment of Male Infertility

Who Can Participate

Age: 18Years - 45Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 45 years
  • Male patients with idiopathic infertility diagnosed with asthenozoospermia, oligozoospermia, or oligoasthenozoospermia
  • No pregnancy achieved after at least one year of unprotected intercourse with the same partner
Not Eligible

You will not qualify if you...

  • Absence of spermatozoa (azoospermia) or very low sperm count (< 5 million sperm/ml)
  • History of testicular torsion or prostatitis
  • Urinary retention or infections
  • Current drug consumption
  • Undergoing hormone treatments
  • Recent surgeries
  • Diabetes
  • Kidney or liver disease
  • Presence of leukocytosis
  • Use of antioxidant supplements in the last 3 months
  • Body mass index (BMI) over 30 kg/m2
  • Endocrine disorders including hypo- or hyperthyroidism
  • Chromosomal anomalies such as XX, XYY, or XXY
  • Treatment with anticoagulants
  • Previous radiotherapy or chemotherapy
  • Participation in another clinical study that may affect this study's objectives

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Clinic

Barcelona, Spain, 08036

Actively Recruiting

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Research Team

C

Carlos Infante

CONTACT

C

Carlos Unamunzaga

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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