Actively Recruiting
Study of Viral Transduction of Human Auditory Sensory Cells for the Development of Gene Therapy
Led by Institut Pasteur · Updated on 2024-09-19
100
Participants Needed
2
Research Sites
417 weeks
Total Duration
On this page
Sponsors
I
Institut Pasteur
Lead Sponsor
A
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsor
AI-Summary
What this Trial Is About
Gene therapy is a promising strategy to treat hearing loss and vestibular disorders, and Associated adenovirus (AAV) is shown as a good viral vector for inner ear therapy in animal models. This study aims to study in vitro viral transduction of AAV in human inner ear cells, collected during non-conservative surgeries for vestibular schwannoma.
CONDITIONS
Official Title
Study of Viral Transduction of Human Auditory Sensory Cells for the Development of Gene Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient 18 years old or older
- Surgery planned for non-conservative removal of vestibular schwannoma as decided by the surgeon and patient
- Informed consent given
- Patient has French social protection (AME excluded)
You will not qualify if you...
- Tumor has spread into the inner ear (intravestibular or intra-cochlear extension)
- Pregnant women
- Patients under administrative control
- Medical conditions preventing participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Hôpital de Bicêtre
Le Kremlin-Bicêtre, Île-de-France Region, France, 94270
Actively Recruiting
2
Hôpital Pitié-Salpétrière
Paris, Île-de-France Region, France, 75015
Actively Recruiting
Research Team
G
Ghizlene Lahlou
CONTACT
S
Saaid Safieddine
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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