Actively Recruiting
A Study of WX390 in Patients With Advanced Solid Tumors
Led by Shanghai Jiatan Pharmatech Co., Ltd · Updated on 2024-11-19
70
Participants Needed
1
Research Sites
265 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate the efficacy and safety of WX390 in patients with advanced solid tumors. The main questions it aims to answer are: * PFS, OS, DoR at week 48; * antitumor effects at week 24 and week 48. Participants will be treated with WX390 orally, and follow the efficacy and safety evaluation according to the protocol.
CONDITIONS
Official Title
A Study of WX390 in Patients With Advanced Solid Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Histologically or cytologically confirmed advanced solid tumor with prior standard treatment failure
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
- Life expectancy of more than 3 months
- At least one measurable lesion according to RECIST 1.1 criteria
- Adequate organ function
- Signed and dated informed consent form
You will not qualify if you...
- Received anti-cancer therapy within 30 days before starting the study treatment
- Had major surgery within 30 days before starting the study treatment
- Any unresolved toxicity from previous anti-cancer treatments above grade 1 (except hair loss)
- Active interstitial lung disease
- Evidence of active or ongoing serious infection
- Received corticosteroids or other immunosuppressive drugs within 2 weeks before first treatment dose
- Active hepatitis B or C infection
- Unable to take medication orally
- Abuse of alcohol or drugs
- Pregnant or breastfeeding
- Cognitive or psychological conditions affecting compliance
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, China, 200000
Actively Recruiting
Research Team
J
Jiajia Li
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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