Actively Recruiting
A Study of Zimberelimab(GLS-010) Combined With AVD for Newly Diagnosed Early-stage Hodgkin's Lymphoma
Led by Sun Yat-sen University · Updated on 2023-06-18
54
Participants Needed
1
Research Sites
158 weeks
Total Duration
On this page
Sponsors
S
Sun Yat-sen University
Lead Sponsor
G
Guangzhou Gloria Biosciences Co., Ltd.
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a multicenter, open-label single-arm phase II study to evaluate the efficacy and safety of Zimberelimab (GLS-010) combined with AVD for newly diagnosed early-stage Hodgkin's lymphoma under the guidance of PET/CT.
CONDITIONS
Official Title
A Study of Zimberelimab(GLS-010) Combined With AVD for Newly Diagnosed Early-stage Hodgkin's Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with primary classical Hodgkin lymphoma confirmed by tissue analysis
- Disease at stage I or II
- At least one measurable target lesion according to Lugano 2014 criteria
- Age 18 to 45 years, or over 60 years (considering fertility and chemotherapy side effects)
- Performance status (ECOG) of 0 to 3
- Expected survival of at least 3 months
You will not qualify if you...
- Hodgkin's lymphoma of the nodular lymphocyte predominant type
- Scheduled for autologous stem cell transplantation
- Contraindications to radiotherapy
- Central nervous system involvement (meningeal or brain)
- Contraindications to immune checkpoint inhibitors
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Medical Oncology, Sun Yat-Sen University Cancer Center
Guangzhou, Guangdong, China, 510060
Actively Recruiting
Research Team
Z
Zhiming Li
CONTACT
Y
Yu Wang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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