Actively Recruiting
"Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients"
Led by Ain Shams University · Updated on 2025-01-06
100
Participants Needed
1
Research Sites
53 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The role of epigenetic regulators and their dysregulation in cancer have gained much attention recently, as they influence the gene expression of many oncogenes and tumor suppressor genes. Non-coding RNAs (ncRNAs) including (lncRNAs and miRNAs) and chromatin remodeling machinery proteins are key epigenetic regulators playing a key role in carcinogenesis. In addition, they can serve as diagnostic and prognostic markers in many cancer types including breast cancer. Therefore, studying these molecular markers will help in the diagnosis and prognosis as well as in the better understanding of this devastating disease.To the best of our knowledge, This is the first research work measuring the expression level of UPK1A-AS1 and/or UNC5B-AS1 in breast cancer clinical samples. These data could provide a promising approach in introducing a novel markers that help in the diagnosis and prognosis of breast cancer and provide a potential targets for gene therapy.
CONDITIONS
Official Title
"Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients"
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Egyptian female breast cancer patients aged 18 years and above
- Newly diagnosed with breast cancer
You will not qualify if you...
- Presence of blood diseases
- Having any cancer other than breast cancer
- Diagnosis of liver cirrhosis
- Having uterine or urinary bladder diseases
- Evidence of distant metastases in breast cancer patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Faculty of pharmacy, Ain Shams University
Cairo, Egypt
Actively Recruiting
Research Team
S
Sherihan Galal, phD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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