Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06492083

A Stuty on the Treatment and Nursing Care of CIPN Patients With Traditional Chinese Medicine Hot Package

Led by The Fourth Affiliated Hospital of Zhejiang University School of Medicine · Updated on 2025-02-17

90

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The combination of platinum and taxane drugs has a chemotherapy-induced peripheral neuropathy (CIPN) rate of 73% to 83%. Its symptoms can not only limit daily activities and cause a variety of accidental injuries, but also easily cause negative emotions and seriously affect the quality of life. Modern Western medicine lacks effective clinical intervention methods, and the treatment of acupuncture points with traditional Chinese medicine is simple to operate, easy to observe adverse reactions, and is suitable for continuous self-treatment outside the hospital after training, saving patients time to travel to and from the hospital, and high patient acceptance. Due to the similarity of the pathogenesis of some traditional Chinese and Western medicine in CIPN and the effectiveness of its application in patients with DPN, this study evaluated the effect of specific formulations of Chinese medicine on CIPN by comparing the degree of nerve damage between the following formulations of Chinese medicine hot packs in patients with platinum combined with paclitaxel chemotherapy and the control group.

CONDITIONS

Official Title

A Stuty on the Treatment and Nursing Care of CIPN Patients With Traditional Chinese Medicine Hot Package

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults expected to survive with tumor for more than 1 year
  • Receiving platinum combined with paclitaxel chemotherapy for the first time
  • Voluntarily agree to participate and sign a consent form
Not Eligible

You will not qualify if you...

  • Allergic to platinum, paclitaxel, or Chinese herbal medicine ingredients
  • Have diabetes mellitus, Raynaud's syndrome, or central or peripheral nerve disease symptoms
  • Unable to judge own symptoms
  • Pregnant or lactating women
  • Have advanced rheumatoid arthritis, severe joint deformity, or incapacitation
  • Have other immune system diseases
  • Have not completed chemotherapy regimen
  • Missed hot acupuncture point treatment 3 or more times per week
  • Incomplete clinical data collection
  • Voluntarily withdrew or unwilling to continue treatment

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine

Yiwu, Zhejiang, China, 322000

Actively Recruiting

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Research Team

L

Lin Dong, Bachelor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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