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ID06309511

Study of Subendocardial Viability Ratio Using Non-Invasive Arterial Tonometry in Adults With Hypertension

Led by Istituto Auxologico Italiano · Updated on 2025-08-03

3000

Participants Needed

5

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating the Subendocardial Viability Ratio SEVR in patients with hypertension using a non-invasive arterial tonometry technique. The goal is to understand factors that influence SEVR and explore its potential in predicting cardiovascular problems and death related to high blood pressure. This observational study is sponsored by Istituto Auxologico Italiano and focuses on patients at Arterial Hypertension Centers. Participants will undergo arterial transcutaneous tonometry to measure the SEVR, calculated from the shape of the central pressure wave. This ratio compares the diastolic pressure-time index and the systolic pressure-time index from carotid pressure curves. Measurements will be taken at recruitment, then at 1, 2, 3, and 4 years of follow-up to track changes over time. During the study, participants will have their SEVR assessed along with collection of body measurements and health data stored in a database. The main outcome measured is the Buckberg index at multiple time points. This long-term observation aims to provide insights into cardiovascular risks in hypertension without altering participants usual care. The study is planned to continue until the end of 2026.

CONDITIONS

Brief Title

Subendocardial Viability Ratio in Hypertension

Research Team

P

Paolo Salvi, MD

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