Actively Recruiting
Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy
Led by University of Missouri-Columbia · Updated on 2025-05-04
200
Participants Needed
1
Research Sites
358 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to determine a grading system for inflammation in lumbar disc herniation and which groups, if any, benefit most from the administration of an intra-operative epidural steroid.
CONDITIONS
Official Title
Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Presenting to the University of Missouri hospital system with clinical signs of lumbar disc herniation
- Failed conservative treatments including rest, anti-inflammatory medications, and physical therapy
- Presence of radiculopathy with positive tension signs or sensory/motor neurological deficits
- Recent MRI confirming a single-level lumbar disc herniation matching clinical symptoms
You will not qualify if you...
- Having spinal stenosis, segmental instability, or spondylolisthesis along with disc herniation
- Previous surgery at the affected lumbar level or recurrent disc herniation
- Underlying conditions affecting steroid response such as immunocompromise or chronic steroid use
- Pregnancy confirmed by a pregnancy test prior to enrollment
- Diagnosis or symptoms suggestive of cauda equina syndrome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Missouri Orthopaedic Institute
Columbia, Missouri, United States, 65202
Actively Recruiting
Research Team
V
Vickci Jones, MEd, CCRP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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