Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT07309601

Sucrase-Isomaltase (SI) Genes and Meal Load

Led by Region Skane · Updated on 2026-04-29

70

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this interventional study is to examine whether those patients with irritable bowel syndrome (IBS) and a reduced abitility do degrade starch and sugar (lowe levels of enzymes) have lower raise in blood glucose after a meal than those with normal expression of enzymes. We also want to examine whether those IBS patients with reduced enzyme levels have increased bowel symptom in relation to this meal. The main questions it aims to answer are: Does reduced ability to degrade starch and sugar due to less enzyme activity lead to lower increase in blood glucose after a meal? Does reduced ability to degrade starch and sugar due to less enzyme activity lead to increased bowel symptoms after a meal?

CONDITIONS

Official Title

Sucrase-Isomaltase (SI) Genes and Meal Load

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of irritable bowel syndrome (IBS)
  • Genetic testing for sucrase-isomaltase enzyme genes completed in previous dietary studies
Not Eligible

You will not qualify if you...

  • Diagnosis of inflammatory bowel disease, celiac disease, bile salt malabsorption, gastroenteritis, or enteric dysmotility
  • Severe food allergy
  • Serious heart, lung, cardiovascular, malignant, or mental illness
  • Ongoing eating disorder
  • Pregnancy
  • Recent major gastrointestinal surgery
  • Alcohol and/or drug addiction

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Skåne University Hospital

Malmö, Skåne County, Sweden, 20502

Actively Recruiting

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Research Team

B

Bodil Ohlsson C Professor, MD, PhD

CONTACT

M

Mauro D'Amato Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Sucrase-Isomaltase (SI) Genes and Meal Load | DecenTrialz