Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06136585

Sugammadex Vs Neostigmine in Reversing Neuromuscular Blocks in Outpatient ERCP. A Randomized, Double-Blinded Trial

Led by The Cleveland Clinic · Updated on 2025-12-15

80

Participants Needed

1

Research Sites

134 weeks

Total Duration

On this page

Sponsors

T

The Cleveland Clinic

Lead Sponsor

M

Merck Sharp & Dohme LLC

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators propose a single-center, assessor-Blinded, parallel group randomized trial to compare the efficacy of reversal of rocuronium induced neuromuscular blockade by sugammadex versus neostigmine in patients undergoing Endoscopic retrograde cholangiopancreatography at Cleveland Clinic Fairview Hospital.

CONDITIONS

Official Title

Sugammadex Vs Neostigmine in Reversing Neuromuscular Blocks in Outpatient ERCP. A Randomized, Double-Blinded Trial

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • American Society of Anesthesiologist physical status 3 or 4
  • Scheduled for outpatient endoscopic retrograde cholangiopancreatography (ERCP)
Not Eligible

You will not qualify if you...

  • Difficult airway
  • Neuromuscular disorders such as ALS, Botulism, Myasthenia Gravis, Lambert-Eaton syndrome
  • End stage renal disease requiring dialysis
  • Pregnancy or breastfeeding
  • Allergy to fentanyl
  • Allergy to neuromuscular blocking drugs such as rocuronium
  • Allergy to neuromuscular reversal drugs such as sugammadex or neostigmine
  • Allergy to glycopyrrolate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cleveland Clinic Fairview Hospital

Cleveland, Ohio, United States, 44111

Actively Recruiting

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Research Team

S

Sabry Ayad, MD

CONTACT

E

Erica Linna, RN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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