Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06481033

Suicide Specific Rumination in Veterans

Led by VA Office of Research and Development · Updated on 2025-07-31

15

Participants Needed

1

Research Sites

126 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Few treatments target core features of suicidal thoughts and behaviors in Veterans. Real-time functional magnetic resonance imaging neurofeedback can provide information regarding brain activation associated with suicide-specific rumination, defined as a "repetitive mental fixation on one's suicidal thoughts and intentions." The goal of this feasibility study is for Veterans to learn strategies for modulating activity within brain regions that have been demonstrated to contribute to the maintenance of rumination, as they receive neurofeedback feedback signals from the brain.

CONDITIONS

Official Title

Suicide Specific Rumination in Veterans

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • U.S. military veteran between 18-65 years old
  • Negative pregnancy test on MRI scan days
  • Score greater than or equal to 10 on the Suicide Rumination Scale
  • Clinically stabilized on psychotropic medications
  • Engaged in mental health care treatment
  • Able to provide written, informed consent
Not Eligible

You will not qualify if you...

  • Major medical or neurological disorders that could interfere with treatment
  • Moderate or severe traumatic brain injury
  • Current imminent suicide risk as determined by psychiatric interview and clinical judgment
  • Any current psychotic disorder
  • MRI contraindications
  • Substance use disorder other than mild alcohol or cannabis use disorder
  • Pregnant or trying to become pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

James J. Peters VA Medical Center, Bronx, NY

The Bronx, New York, United States, 10468-3904

Actively Recruiting

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Research Team

P

Philip R Szeszko, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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