Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT07117890

Sunvozertinib Treatment in Untreated Advanced NSCLC With EGFR Uncommon Mutations

Led by Fudan University · Updated on 2025-12-24

34

Participants Needed

1

Research Sites

120 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a single arm study to access the anti-tumor efficacy and safety of sunvozertinib in untreated advanced NSCLC patients with EGFR uncommon mutations.

CONDITIONS

Official Title

Sunvozertinib Treatment in Untreated Advanced NSCLC With EGFR Uncommon Mutations

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years old or older
  • Histologically or cytologically confirmed non-squamous NSCLC with documented EGFR uncommon mutations from a local laboratory, including at least one uncommon mutation (excluding EGFR 19del, L858R, T790M, Exon 20 insertions) or compound mutations involving uncommon EGFR mutations
  • Predicted life expectancy of 12 weeks or more
  • Measurable disease according to RECIST 1.1
Not Eligible

You will not qualify if you...

  • Previous systemic anti-tumor therapy
  • History of malignant tumors within the past 2 years
  • Any severe or poorly controlled systemic disease as judged by the investigator
  • Active infections

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fudan university shanghai cancer center

Shanghai, China

Actively Recruiting

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Research Team

J

Jialei Wang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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