Actively Recruiting
Super-Resolution Ultrasound of the Brain in 3D
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2024-09-19
20
Participants Needed
1
Research Sites
45 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
C
Centre National de la Recherche Scientifique, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this proof of concept study is to determine if the visualization of the middle cerebral artery and its perforators, through 3D transtemporal ultrasound imaging, is possible thanks to an off-line analysis by 3D ultrasound localization microscopy. Visualization of these vessels would allow us to conclude on the presence, or absence, of an ischemic stroke in the region of the middle cerebral artery. To answer the question asked, 20 participants who suffered a stroke will carry out a transtemporal ultrasound examination specifically for research in the 7 days following his stroke. The data obtained will be analyzed by the CNRS medical imaging laboratory, in order to characterize the presence of a stroke and to compare the data obtained with that of standard examinations (CT and MRI).
CONDITIONS
Official Title
Super-Resolution Ultrasound of the Brain in 3D
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient aged 18 and over
- Hospitalized patient with ischemic stroke in the deep territory of the middle cerebral artery
- Patient with lesion observable on MRI
- Patient included between 24 hours and 7 days after the ischemic stroke
- Patient with a temporal window which allows soundproofing of the polygon of Willis and the middle cerebral artery
- Patient having signed free, informed and written consent
- Patient affiliated to a social security system (excluding AME)
You will not qualify if you...
- Contralateral middle cerebral artery territory stroke or contralateral middle cerebral artery occlusion
- Patient with contraindication to Doppler ultrasound with contrast (right-left shunt, severe pulmonary arterial hypertension)
- Patient with hypersensitivity to the active princip of Sonovue (sulfur hexafluoride) or these excipients
- Patient with uncontrolled systemic hypertension
- Patient with respiratory distress syndrome
- Patient under guardianship or curatorship
- Pregnant or breastfeeding patient (positive blood pregnancy test during hospitalization)
- Patient with damaged skin at the temporal level
- Patient having presented in the 7 days preceding inclusion an acute coronary syndrome or suffering from unstable ischemic heart disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hôpital Bichat
Paris, Île-de-France Region, France, 75018
Actively Recruiting
Research Team
E
Elena MESEGUER, Dr
CONTACT
M
Marine CAMUS, Mrs
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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