Actively Recruiting

Age: 18Years - 60Years
All Genders
NCT06513676

Super Selective Adrenal Artery Embolization for Primary Aldosteronism: a Prospective Cohort Study(SAAE-PA)

Led by Xinjiang Medical University · Updated on 2024-07-23

500

Participants Needed

1

Research Sites

224 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of this study was to evaluate the efficacy and safety of adrenal vein blood extraction for primary aldosteronism classification and adrenal artery embolization in the treatment of primary aldosteronism, to provide new evidence plan for the diagnosis and treatment of primary aldosteronism, and to promote the development of adrenal artery embolization as a new treatment for primary aldosteronism.

CONDITIONS

Official Title

Super Selective Adrenal Artery Embolization for Primary Aldosteronism: a Prospective Cohort Study(SAAE-PA)

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18-60 years old
  • Diagnosed with primary hyperaldosteronism according to the 2016 International Endocrine Society clinical guidelines
  • Refusal of medication due to side effects, refusal of adrenal surgery due to surgical risk, or persistent hyperaldosteronism and adrenal cortex insufficiency after surgery
  • Voluntary acceptance of adrenal artery embolization after being fully informed of all current treatment options for primary aldosteronism
Not Eligible

You will not qualify if you...

  • History of severe allergic reaction to contrast media
  • Serious liver disease complications such as thrombocytopenia or esophageal variceal bleeding
  • Renal insufficiency with serum creatinine over 176 mmol/L or low estimated glomerular filtration rate
  • Other secondary hypertension causes including pheochromocytoma, hypercortisolism, renal vascular hypertension, renin-secreting tumor, renal parenchymal hypertension, drug-induced hypertension, pregnancy-related hypertension
  • Hereditary diseases such as false aldosteronism, Bartter syndrome, familial hypokalemia and hypomagnesemia
  • Stroke, heart attack, or stent placement within the past 3 months
  • Severe other medical conditions like grade IV heart failure, acute infections, autoimmune diseases, or cancer
  • Participation in other clinical trials within the last 3 months
  • Current pregnancy, breastfeeding, or planning pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The First Affiliated Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, China, 630000

Actively Recruiting

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Research Team

X

Xiang Xie

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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