Actively Recruiting
Supplemental Postoperative Bupivacaine Following Non-Surgical Endodontic Treatment
Led by New York University · Updated on 2026-04-13
150
Participants Needed
1
Research Sites
112 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study will investigate the impact of an additional injection of long-acting anesthetic on pain level, quality of life, and use of pain medication after a nonsurgical endodontic treatment. The long-acting anesthetic will be compared to a mock injection group and a group with no additional anesthetic to determine any differences in effects.
CONDITIONS
Official Title
Supplemental Postoperative Bupivacaine Following Non-Surgical Endodontic Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Medical ASA Class I or II
- Patients above 18 years old
- Patients with a blood pressure below 160/100
- Patients planned and agreeing to emergency endodontic therapy or non-surgical root canal therapy with symptomatic irreversible pulpitis
- Ability to understand and complete study protocols, consent, and questionnaires in English
You will not qualify if you...
- Medical ASA Class III or higher
- Use of tobacco or nicotine products within 48 hours before and after treatment
- Use of marijuana or illicit drugs within 48 hours before and after treatment
- Prior use of opioids to control pain
- Pregnancy
- Blood pressure of 160/100 or greater
- Known allergy to local anesthetics of the amide group or components in the anesthetic solutions
- More than one tooth with odontogenic pain at screening
- Inability to consent or understand questionnaires
- Receipt of 4 or more carpules of anesthetic (Lidocaine and/or Septocaine) during standard care
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
New York University College of Dentistry
New York, New York, United States, 10010
Actively Recruiting
Research Team
L
Lorel E Burns, DDS
CONTACT
N
NYUSOM IRB
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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