Actively Recruiting
Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques
Led by Erzincan University · Updated on 2026-01-13
102
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Postoperative pain following total knee arthroplasty (TKA) is a significant clinical problem that delays early mobilization, reduces patient satisfaction, and increases analgesic requirements. The adductor canal block (ACB), which aims to provide analgesia while preserving motor function, is widely used in postoperative pain management after TKA. However, clinical and anatomical studies have demonstrated that ACB is effective only in the anteromedial sensory innervation of the knee and does not adequately block pain originating from the posterior knee capsule. This limitation reduces analgesic effectiveness, particularly in patients with a prominent posterior pain component. The sciatic nerve block has long been considered the gold standard for managing posterior knee pain. However, due to disadvantages such as motor weakness and delayed rehabilitation, current pain management protocols increasingly favor motor-sparing and complementary approaches such as the Biceps Femoris Short Head (BiFeS) block and the Interspace Between the Popliteal Artery and the Capsule of the posterior Knee (IPACK) block for posterior knee analgesia. In light of this information, the aim of our study is to guide clinical practice by comparing the postoperative analgesic efficacy, motor function outcomes, and patient satisfaction associated with sciatic nerve, BiFeS, and IPACK block techniques-each administered as a supplement to the adductor canal block-in patients undergoing total knee arthroplasty, with the ultimate goal of determining the optimal block combination for postoperative pain control.
CONDITIONS
Official Title
Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients classified as American Society of Anesthesiologists (ASA) physical status I-III
- Patients undergoing primary total knee arthroplasty
- Patients undergoing unilateral total knee arthroplasty
- Patients between 18 and 75 years of age
You will not qualify if you...
- Patients classified as American Society of Anesthesiologists (ASA) physical status IV or higher
- Patients undergoing revision total knee arthroplasty
- Patients undergoing bilateral total knee arthroplasty
- Patients with neuromuscular disease
- Patients who decline to participate in the study
- Patients with cognitive dysfunction
- Patients with known drug allergies
- Patients with a history of local anesthetic systemic toxicity
- Patients with neurological dysfunction
- Patients with bleeding diathesis
- Pregnant patients
AI-Screening
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Trial Site Locations
Total: 1 location
1
Erzincan Binali Yıldırım Üniversitesi
Erzincan, Merkez, Turkey (Türkiye), 24000
Actively Recruiting
Research Team
M
mustafa somunkıran, anesthesiology resident
CONTACT
F
fethi akyol, Assistant Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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