Actively Recruiting
Supplementation With Sirtuin Activators in Women With Increased Body Weight
Led by Poznan University of Life Sciences · Updated on 2026-02-19
120
Participants Needed
1
Research Sites
72 weeks
Total Duration
On this page
Sponsors
P
Poznan University of Life Sciences
Lead Sponsor
P
Poznan University of Medical Sciences
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are: Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing? Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status. Participants will: Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.
CONDITIONS
Official Title
Supplementation With Sirtuin Activators in Women With Increased Body Weight
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female
- Age between 40 and 65 years
- Overweight or obese with BMI greater than 25 kg/m2
You will not qualify if you...
- Male
- BMI less than 25 kg/m2
- Taken sirtuin activators within 3 months prior to the study
- Pregnant or breastfeeding
- Recently dieting or on calorie-restricted diet
- Receiving medication to treat obesity, diabetes, or high cholesterol
- Had bariatric surgery
- Diagnosed with diabetes
- Diagnosed with cancer
- Have chronic kidney, liver, or autoimmune diseases
- Have alcohol addiction
AI-Screening
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Trial Site Locations
Total: 1 location
1
Poznan University of Life Sciences
Poznan, Poland
Actively Recruiting
Research Team
A
Agata Chmurzynska, Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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