Actively Recruiting
Supportive-Expressive and Emotion-Focused Treatment for Depression
Led by University of Haifa · Updated on 2026-05-07
124
Participants Needed
1
Research Sites
339 weeks
Total Duration
On this page
Sponsors
U
University of Haifa
Lead Sponsor
I
Israel Science Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will explore the mechanisms of change that are activated when individuals receive a treatment that targets their weakness and the mechanisms activated when the treatment capitalize on their strength. Patients will be assigned to one of two types of psychotherapies in treating people with a major depression disorder, expressive-supportive vs. emotion-focused treatment. Their ability to benefit from treatment based on their pre-treatment levels of insight and emotional processing will be examined. This is a four-month protocol, with a 2 year follow up period.
CONDITIONS
Official Title
Supportive-Expressive and Emotion-Focused Treatment for Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meeting major depressive disorder diagnostic criteria using the structured clinical interviews for Diagnostic and Statistical Manual of Mental Disorders-5 and scoring more than 14 on the 17-item Hamilton rating scale for depression at two evaluations (one week apart) (Hamilton, 1967).
- If on medication, patients' dosage must be stable for at least three months prior to entering the study, and they must be willing to maintain stable dosage for the duration of treatment
- Age between 18 and 65
- Hebrew language fluency
- Provision of written informed consent.
You will not qualify if you...
- Current risk of suicide or self-harm
- current substance abuse disorders
- current or past schizophrenia or psychosis, bipolar disorder, or severe eating disorder requiring medical monitoring
- history of organic mental disease
- currently in psychotherapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Haifa
Haifa, Israel
Actively Recruiting
Research Team
S
Sigal Zilcha-Mano, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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