Actively Recruiting

Early Phase 1
Age: 18Years +
All Genders
ID07145008

Suprachoroidal Triamcinolone in Macular Edema for Patients With Non-Infectious Uveitis Resistant to Subtenon Triamcinolon

Led by University of Baghdad · Updated on 2025-08-28

20

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating whether a suprachoroidal injection of triamcinolone can treat vision-threatening swelling in the center of the retina, called macular edema, caused by non-infectious uveitis. This study focuses especially on patients who did not improve after receiving a standard steroid injection around the eye (sub-Tenon injection). The main questions include whether vision improves on the eye chart and if retinal swelling decreases within three months after the injection. Participants will receive one suprachoroidal triamcinolone injection delivered using a custom-made device with controlled needle depth under anesthetic eye drops in a sterile setting. The study includes a pretreatment check with vision tests, slit-lamp examination, and an OCT retinal scan. Follow-up visits will occur about one month and three months after treatment to repeat vision tests and OCT scans. During the study, participants will be monitored for vision improvement and reduction in retinal thickness. They are asked to contact the clinic if they experience pain, redness, new floaters, or worsening vision. The primary outcome measure is visual acuity improvement at three months, with central macular thickness as a secondary outcome. The total participation duration includes screening, treatment, and follow-up over three months.

CONDITIONS

Brief Title

Suprachoroidal Triamcinolone in Macular Edema for Patients With Non-Infectious Uveitis Resistant to Subtenon Triamcinolon

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Non-infectious uveitis complicated with macular edema
  • Uveitic macular edema of less than four months' duration
  • Macular edema persisted despite lack of intra-ocular inflammation
  • No response to posterior sub-Tenon triamcinolone acetonide injections
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Epiretinal membrane-associated macular edema
  • Age below 18 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Up to 3 months

Participants receive suprachoroidal triamcinolone acetonide injection using a custom delivery system to treat macular edema.

1 baseline visit and several follow-up visits over 3 months

Trial Site Locations

Total: 1 location

1

Ibn Al-Haitham Eye Teaching Hospital

Baghdad, Iraq, 10064

Actively Recruiting

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Research Team

M

Mohammed Suhail Al-Salam

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Frequently Asked Questions

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