Actively Recruiting
Suprachoroidal Triamcinolone in Macular Edema for Patients With Non-Infectious Uveitis Resistant to Subtenon Triamcinolon
Led by University of Baghdad · Updated on 2025-08-28
20
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating whether a suprachoroidal injection of triamcinolone can treat vision-threatening swelling in the center of the retina, called macular edema, caused by non-infectious uveitis. This study focuses especially on patients who did not improve after receiving a standard steroid injection around the eye (sub-Tenon injection). The main questions include whether vision improves on the eye chart and if retinal swelling decreases within three months after the injection. Participants will receive one suprachoroidal triamcinolone injection delivered using a custom-made device with controlled needle depth under anesthetic eye drops in a sterile setting. The study includes a pretreatment check with vision tests, slit-lamp examination, and an OCT retinal scan. Follow-up visits will occur about one month and three months after treatment to repeat vision tests and OCT scans. During the study, participants will be monitored for vision improvement and reduction in retinal thickness. They are asked to contact the clinic if they experience pain, redness, new floaters, or worsening vision. The primary outcome measure is visual acuity improvement at three months, with central macular thickness as a secondary outcome. The total participation duration includes screening, treatment, and follow-up over three months.
CONDITIONS
Brief Title
Suprachoroidal Triamcinolone in Macular Edema for Patients With Non-Infectious Uveitis Resistant to Subtenon Triamcinolon
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Non-infectious uveitis complicated with macular edema
- Uveitic macular edema of less than four months' duration
- Macular edema persisted despite lack of intra-ocular inflammation
- No response to posterior sub-Tenon triamcinolone acetonide injections
- Age 18 years or older
You will not qualify if you...
- Epiretinal membrane-associated macular edema
- Age below 18 years
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 3 months
Participants receive suprachoroidal triamcinolone acetonide injection using a custom delivery system to treat macular edema.
1 baseline visit and several follow-up visits over 3 months
Trial Site Locations
Total: 1 location
1
Ibn Al-Haitham Eye Teaching Hospital
Baghdad, Iraq, 10064
Actively Recruiting
Research Team
M
Mohammed Suhail Al-Salam
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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