Actively Recruiting
Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery
Led by University of North Carolina, Chapel Hill · Updated on 2025-10-24
100
Participants Needed
1
Research Sites
129 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Orthopedic wrist procedures often cause significant postoperative pain. A supraclavicular nerve block is an effective and proven method to help reduce postoperative pain and decrease opioid use around the time of upper extremity surgery. Liposomal bupivacaine (Exparel) has been approved for use around the brachial plexus, but its analgesic efficacy has limited data. The investigators' goal is to evaluate the effectiveness of Exparel as compared to plain bupivacaine. The investigators hope to ensure the quality of pain control around the time of distal radius fracture repair and reduce the variability of care at the investigators institution by prospectively and rigorously collecting perioperative data during this study.
CONDITIONS
Official Title
Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than or equal to 18
- Scheduled for orthopedic wrist surgery at University of North Carolina at Chapel Hill
You will not qualify if you...
- Contraindications to regional anesthesia
- Emergent surgery (open fractures treated emergently)
- Significant peripheral neuropathy or neurological disorder affecting the upper extremity
- Pregnancy
- Cognitive or psychiatric condition affecting patient assessment or ability to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UNC Chapel Hill
Chapel Hill, North Carolina, United States, 27514
Actively Recruiting
Research Team
J
Jay Schoenherr, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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