Actively Recruiting

Phase Not Applicable
Age: 0Days - 1Day
All Genders
NCT07419438

Supraglottic Airway for Resuscitation in Preemies

Led by University of Pennsylvania · Updated on 2026-04-17

20

Participants Needed

1

Research Sites

28 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this single-arm intervention trial is to learn whether using a supraglottic airway (SA) as the primary interface for positive pressure ventilation (PPV) is feasible during delivery room resuscitation of premature infants. This study will be conducted in premature infants born between 29 0/7 and 33 6/7 weeks' gestation who require PPV at birth. The main question it aims to answer is: Is it feasible to use a supraglottic airway as the primary interface to provide effective PPV during delivery room resuscitation in 29 0/7 to 33 6/7 weeks' gestation premature infants? Participants will (1)Be screened prenatally and have informed consent obtained from the birth parent prior to delivery; (2)Be rescreened for eligibility on the day of delivery before receiving the study intervention; (3)Receive PPV using a supraglottic airway as the primary ventilation interface if resuscitation is required at birth; and (4)Have clinical and procedural data collected during delivery room resuscitation and for up to 24 hours after birth.

CONDITIONS

Official Title

Supraglottic Airway for Resuscitation in Preemies

Who Can Participate

Age: 0Days - 1Day
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Gestational age 29 0/7 to 33 6/7 weeks at birth
  • Estimated fetal weight /= 1000 grams at birth
  • Clinical decision to initiate PPV
  • Parental informed consent
Not Eligible

You will not qualify if you...

  • Major anomalies or aneuploidy
  • Palliative care planned or considered
  • Not resuscitated in the infant resuscitation room

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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3
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Trial Site Locations

Total: 1 location

1

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

S

Sura Lee

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Supraglottic Airway for Resuscitation in Preemies | DecenTrialz