Actively Recruiting
The Supraspinal Control of Lower Urinary Tract Function in Patients with Orthotopic Sigmoid Neobladder.
Led by Zhujiang Hospital · Updated on 2024-12-04
40
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Orthotopic sigmoid neobladder surgery is one of the ideal urinary diversion methods after radical cystectomy.In recent years, functional imaging studies have revealed brain regions related to urinary system function, but brain activity of lower urinary tract function in neobladder patients is still unclear.The aim of this study is to explore the brain activity of urination intention and self-controlled urination behavior in patients with orthotopic sigmoid neobladder by task-state functional magnetic resonance imaging (fMRI).
CONDITIONS
Official Title
The Supraspinal Control of Lower Urinary Tract Function in Patients with Orthotopic Sigmoid Neobladder.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be right-handed
- At least 3 months have passed since orthotopic sigmoid neobladder surgery
- No contraindications for undergoing functional MRI (fMRI) examination
- Voluntarily agree and sign informed consent
You will not qualify if you...
- History of bladder radiotherapy
- History of prostate cancer
- Presence of diseases affecting abdominal pressure
- History of abnormal brain anatomy, brain surgery, brain tumor, or brain radiotherapy
- History of mental disorders, Parkinson's disease, Alzheimer's disease, epilepsy, cerebral infarction, or cerebral hemorrhage
- Claustrophobia or having metal implants unsuitable for fMRI
- Diseases affecting lower urinary tract function such as spinal cord injury or diabetic peripheral neuropathy
- Urethral stricture
- Refusal to sign informed consent for clinical projects
- Other conditions deemed unsuitable by the investigator
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Zhujiang Hospital of Southern Medical University
Guangzhou, Guangdong, China, 510000
Actively Recruiting
Research Team
C
Chunxiao Liu
CONTACT
Y
Yuanxing Huang
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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