Actively Recruiting
SURGE: Supporting UnderRepresented Minorities in Genomics-based Cancer Trial Enrollment (Intervention)
Led by Nadine McCleary, MD, MPH · Updated on 2025-11-05
210
Participants Needed
3
Research Sites
30 weeks
Total Duration
On this page
Sponsors
N
Nadine McCleary, MD, MPH
Lead Sponsor
B
Bristol-Myers Squibb
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying ways to improve enrollment of underrepresented minority patients in genomic testing for cancer clinical trials. This study focuses on patients with advanced gastrointestinal, hematologic, or thoracic cancers who face barriers like low medical literacy and unmet social needs. The goal is to see if video education, with or without personalized patient navigation, can help these patients decide about tumor genomic testing, which is important for accessing precision therapies and trials. Participants are randomly assigned to one of three groups: one group receives standard care, another watches an informational video, and a third group receives both the video and one-on-one patient navigation support. The intervention includes a text message questionnaire to assess awareness and interest in clinical trials before the intervention. This pilot study is conducted at several academic and community oncology sites. During the study, participants complete questionnaires via text or phone and may watch educational videos and interact with patient navigators. The main measure is whether participants undergo genomic testing within 90 days of enrollment. Researchers also track how patients interact with the intervention and how acceptable the questionnaire method is within 30 days. The study runs until July 2028, with safety and consent carefully monitored throughout.
CONDITIONS
Brief Title
SURGE: Supporting UnderRepresented Minorities in Genomics-based Cancer Trial Enrollment (Intervention)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult (age 18 years or older)
- Black, Latinx, OR older adult (age 70 years or older)
- Scheduled for a new patient consultation
- Suspected or confirmed advanced malignancy requiring active treatment
- Gastrointestinal, hematologic, or thoracic cancer
- Patient at specified DFCI and satellite sites
You will not qualify if you...
- Malignancy or former malignancy that requires only surveillance
- Not continuing care at a participating DFCI site
- Speaks a language other than English or Spanish
- Unable to provide consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (via text or phone)
Duration - Up to 30 days
Participants receive an informational video with or without one-on-one patient navigation to support decision-making about genomic tumor testing.
1 to 2 visits depending on intervention arm
Duration - Up to 30 days
Participants who receive standard of care are observed during this period without additional intervention.
Visits as part of routine care
Duration - Up to 90 days
Participants undergo monitoring of genomic testing uptake within 90 days of enrollment.
Visits as part of routine care
Trial Site Locations
Total: 3 locations
1
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
2
Dana-Farber Cancer Institute at St. Elizabeth's Medical Center
Brighton, Massachusetts, United States, 02135
Actively Recruiting
3
Dana-Farber Cancer Instiute - Merrimack Valley
Methuen, Massachusetts, United States, 01844
Not Yet Recruiting
Research Team
N
Nadine J McCleary, MD MPH
N
Nadine J McCleary, MD MPH
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
3
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