Actively Recruiting
Surgery Alone Verus Sugery Combined with Dose-reduced Radiotherapy for Newly Diagnosed Stage I Nasopharyngeal Carcinoma
Led by Ming-Yuan Chen · Updated on 2024-11-14
86
Participants Needed
2
Research Sites
261 weeks
Total Duration
On this page
Sponsors
M
Ming-Yuan Chen
Lead Sponsor
F
Fifth Affiliated Hospital, Sun Yat-Sen University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the efficacy and safety of endoscopic nasopharyngectomy combined with retropharyngeal lymph nodes dissection plus bilateral upper neck lymph node dissection or plus postoperative low-dose radiotherapy in newly diagnosed stage Ⅰ nasopharyngeal carcinoma.
CONDITIONS
Official Title
Surgery Alone Verus Sugery Combined with Dose-reduced Radiotherapy for Newly Diagnosed Stage I Nasopharyngeal Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Performance Status Score 0-1 points
- Histologically or cytologically confirmed non-keratinized nasopharyngeal carcinoma (WHO type II or III)
- Stage I nasopharyngeal carcinoma according to UICC/AJCC 8th edition (T1N0M0)
- Adequate organ function including specified blood counts and liver, kidney tests
- Signed informed consent agreeing to follow-up and study procedures
You will not qualify if you...
- Recurrent or metastatic nasopharyngeal carcinoma or any other malignancy
- Severe organ dysfunction or physical disorder preventing surgery or radiotherapy
- Inability to cooperate with follow-up due to psychological, social, domestic, or geographic reasons
- Pregnancy or breastfeeding
- Any condition deemed inappropriate for the trial by the chief physician
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
The Fifth Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China, 516000
Actively Recruiting
2
The Fifth Affiliated Hospital of Sun Yat-sen University
Zhuhai, Guangdong, China, 519000
Actively Recruiting
Research Team
M
Ming-Yuan Chen, MD,PhD
CONTACT
Y
You-Ping Liu, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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