Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT05327517

Surgery or Chemoradiotherapy for Cervical Esophageal Cancer

Led by Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Updated on 2022-04-14

192

Participants Needed

1

Research Sites

351 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To compare surgery with definitive chemoradiotherapy for patients with resectable cervical esophageal squamous cell carcinoma.

CONDITIONS

Official Title

Surgery or Chemoradiotherapy for Cervical Esophageal Cancer

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with resectable cervical esophageal squamous cell carcinoma (cT1b-T4aN0-3M0)
  • Cervical esophageal cancer spreading to the hypopharynx or thoracic esophagus can be included
  • Aged between 18 and 75 years
  • No contraindications for surgery
  • Hemoglobin level at least 90 g/L
  • Leukocyte count at least 4.0 x 10^9/L
  • Absolute neutrophil count at least 1.5 x 10^9/L
  • Platelet count at least 100 x 10^9/L
  • Total bilirubin no higher than 1.5 times the upper limit of normal (ULN)
  • ALT no higher than 2.5 times ULN
  • AST no higher than 2.5 times ULN
  • Serum creatinine no higher than 1.5 times ULN or creatinine clearance rate at least 50 mL/min
  • INR no higher than 1.5 times ULN
  • APTT no higher than 1.5 times ULN
  • No other malignancies
  • Expected complete tumor removal (R0 resection)
  • ECOG performance status 0 or 1
  • Willingness to participate and signed informed consent form
Not Eligible

You will not qualify if you...

  • Presence of other malignancies
  • Mental health disorders
  • Hemorrhagic diseases
  • Patients who cannot undergo surgery
  • Pregnant or lactating women
  • Allergic history to paclitaxel or cisplatin

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cancer Hospital Chinese Academy of Medical Sciences

Beijing, China

Actively Recruiting

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Research Team

Z

Zhen Wang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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