Actively Recruiting

Age: 18Years +
All Genders
NCT07241663

Surgery for Locally Unresectable Pancreatic Cancer

Led by Azienda Ospedaliera di Padova · Updated on 2025-11-26

150

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

Sponsors

A

Azienda Ospedaliera di Padova

Lead Sponsor

U

University of Padova

Collaborating Sponsor

AI-Summary

What this Trial Is About

Pancreatic cancer is a severe disease often diagnosed at an advanced stage, when surgery is not possible. New chemotherapy treatments can sometimes shrink the tumor and make surgery an option. This study aims to understand if surgery after such treatments can improve survival and quality of life in selected patients treated at expert centers.

CONDITIONS

Official Title

Surgery for Locally Unresectable Pancreatic Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients older than 18 years
  • Able to give informed consent
  • Histologically confirmed pancreatic adenocarcinoma
  • Locally advanced pancreatic cancer stage according to NCCN at diagnosis
  • Received at least 4 months of induction chemotherapy
  • Stable disease or partial response after induction therapy according to RECIST 1.1
  • Considered eligible for radical resection by local multidisciplinary team
Not Eligible

You will not qualify if you...

  • Withdrawal of informed consent
  • Tumor characteristics that prevent surgery
  • Significant patient comorbidities that prevent surgery
  • No available abdominal imaging before induction therapy
  • Pathological confirmation of a tumor other than pancreatic ductal adenocarcinoma

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UOC Chirurgia Generale 2, Azienda Ospedale di Padova, Padova, Italy 35128

Padova, Italy

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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